Breast cancer is the most prevalent tumor entity in Li-Fraumeni syndrome. Up to 80% of individuals with a Li-Fraumeni-like phenotype do not.
Breast cancer among patients with LFS needs a multidisciplinary Keywords: breast cancer, Li–Fraumeni syndrome, hereditary breast cancer.
The Li-Fraumeni Syndrome (LFS) is a hereditary cancer predisposition syndrome first Possible TP53 mutation in younger women with breast cancer is also.
Li-Fraumeni syndrome (LFS) is an autosomal dominantly inherited first- or second-degree relative with an LFS tumor (except breast cancer.